In the cannabis world, CBD and liposomes are two of the hottest topics of the moment. But, while just about everyone has heard of CBD and has a basic understanding of what it does, many people are still unaware of the benefits associated with liposomes. In fact, some people may never have even heard of liposomes.
Liposomes are the next major thing in CBD technology. If this is your first time hearing the term, you may immediately think of liposuctions and fat. And, if this is what you were thinking, you wouldn’t be entirely wrong. The root word “lipo” actually means fat, and “soma” means body. The word liposome could thus easily be defined as a body of fat (or pocket of fat).
Liposomes are exactly that – microscopic pockets of fatty tissue that scientists have discovered function as great molecular nutrient transporters. CBD liposomes are a new method of consuming CBD, where rather than smoking CBD directly from a joint or mixing the CBD in inert oils, you ingest it via a liposome. The liposome is basically a tiny sphere of cholesterol that has the ability to be mixed with water-based substances.
This may seem like a confusing and complicated way to administer your dose of CBD, but it’s actually revolutionizing the way that both medicines and food supplements are being taken.
What are Liposomes?
Just like the name suggests, liposomes are small areas of cholesterol (basically fat) which contain naturally occurring phospholipids. Not to make it any more complicated, phospholipids are a type of fats that can form lipid bilayers, like the outer membranes of our cells. Essentially, this means that they are a double-ended fat molecule. One that has a normal, hydrophobic fatty acid, and the other a head consisting of a phosphate group.
While this may sound like ridiculous, unimportant chemistry, it’s actually very significant for medicine, and for being able to understand the benefits of consuming CBD liposomes rather than other forms of CBD, like edibles and oils.
Generally, fats and water do not mix. If you try to mix oil and water, you will find that instead of mixing together as other liquids would, the oil settles on the surface. This happens because of the electron charge of different molecules. Water-based molecules have a positive and negative charge. This means that they are only able to bond with other water-based molecules.
Fat-soluble molecules, on the other hand, essentially have no charge on either end. Therefore, although fatty substances are happy to bond with one another, they are unable to mix with water-based substances.
However, it’s a bit different in the case of phosphate group liposomes. Since liposomes have both the standard hydrophobic, non-electrically charged ends and a hydrophilic end (meaning it likes water), they are able to bridge the gap between water substances and fat.
Basically, this means that liposomes can help fat-based substances to mix with water-based substances. When you consume cannabinoids, like CBD or THC, your body must work to separate the fat-soluble cannabinoids and mix them with the water components of your body – in the same way, that it does with your bloodstream and muscle tissue.
Due to the variation in charge type, this causes some loss when you are consuming cannabinoids, because some of it simply can’t be absorbed by the body. By using liposome capsules, this can be averted.
Benefits of Liposomes?
So now that you know what liposomes are, you’re probably wondering what they’re good for? Why would anyone want to use liposomes rather than taking CBD in the traditional way? Here are the top five benefits of liposomes.
- Delivery Method
Unlike the other well-known drug delivery methods, liposomes work by transporting ingredients past the intestinal membrane and into specific tissues. As they reach the targeted areas in the body, ingredients found inside these tiny spheres are fully protected. Therefore, the bioavailability of nutrients that are delivered through liposomes is particularly high.
Since being successfully exploited by the traditional pharmaceuticals arena, liposomes are now being championed by the nutraceutical and CBD industries. Because they are non-toxic and non-immunogenic, liposomes are considered to be very safe. Also, unlike other carriers that are sometimes used for drug delivery, liposomes are highly biodegradable.
One of the main reasons that liposomes are becoming so popular is because of their safety. Liposomes are made of phospholipids, which means that they are non-immunogenic, non-toxic, and both biocompatible and biodegradable. There are practically no adverse side effects associated with liposomes.
- CBD and Liposomes: A Winning Combination
CBD, in particular, is very well-suited for delivery through liposomes. This is because CBD is non-psychoactive, which means that ingesting it in its unadulterated form won’t bring on any adverse side effects. Essentially, liposomes allow users to receive their optimal amount of CBD with each and every dose.
In its own right, CBD has the potential to be very effective in the treatment of physical and psychological conditions, such as PTSD, chronic pain, and Dravet Syndrome, among many others. But, when encapsulated by liposomes, the CBD has even greater opportunity to provide its full course of benefits on targeted tissues.
It’s possible for CBD to be administered via liposomes in both oral and topical formulations. These methods of intake are both already very popular. When taken via oral consumption, the liposomes allow for more accurate dosing. Since the CBD is safely encapsulated and doesn’t get compromised on route to the targeted tissues, liposomes are able to improve the absorption of CBD greatly. When used in topicals, like ointments and creams, liposomes help the CBD to deeper penetrate the skin for a more profound effect.
- Absorption and Solubility
With people looking to make the most of the health benefits associated with CBD, liposomes offer a unique and effective approach, ensuring a safe passage within the body to ensure that the full benefits are received. More specifically, this unique method of absorption means that the CBD reaches the cells in their purest form.
This results in an increase in potency, which lowers the dosage that is required. Making use of liposomes is one of the very few methods that are able to protect the CBD from being partially destroyed by digestive enzymes.
Scientific studies have found that using liposomes as a delivery method improves the bioavailability of nutrients because it helps to protect the drug in the mucous membranes and gastrointestinal tract. One particular study that was published in 2017 stated that liposomes offer “controllable release,” which means that the drugs are liberated at the right time and in the right place, and this can significantly reduce the administration time, and also avoids toxicity to other organs.
- Activity in the Endocannabinoid System (ECS)
The ECS is the system that runs throughout the body and is responsible for various healing effects and regulatory controls, like appetite, mood, and immune system. The ECS consists of cannabinoid receptors that are triggered by the body’s naturally-produced endocannabinoids.
However, some individuals don’t have enough endocannabinoid receptors. This has been thought to be something that is partially responsible for the development of various conditions, like Alzheimer’s and chronic pain. But more significantly, it means that these people struggle to gain the positive effects of cannabinoids. For these people, in particular, CBD liposomes could be especially helpful.
Because the liposome is made of both fat-compatible and water-compatible molecules, the active compound can be carried into the bloodstream very effectively. This may be helpful in overcoming certain deficiencies that are associated with a deficiency in endocannabinoid receptors.
Liposomes increase the transference rate of CBD into the human body, regardless of what ability the body has to process cannabinoids. This makes liposomes extremely useful for those with an endocannabinoid deficiency.
- Liposomes Play a Key Role in the Future of CBD
Using this state-of-the-art-technology, it’s possible for CBD to move unharmed through the digestive tract until they make it to the intestinal membrane. Traditionally, digestive enzymes then start to break down the CBD molecules, delaying and reducing the amount of CBD that the body is able to absorb.
Not only does liposomal delivery accelerate uptake, but it also improves the potency of CBD oil, even at lower concentrations. Liposomal delivery makes it possible for CBD oils with a 4% concentration to provide the same therapeutic benefits at an even faster rate than oils that are produced under traditional methods and contain a significantly higher level of CBD.
Final Thoughts on CBD Liposomes
Making use of liposomes for delivering CBD is likely to result in a variety of benefits for the consumer. Not only do liposomes deliver higher concentrations of CBD, but it also allows individuals to use less CBD to achieve similar effects as other intake methods.
While a lot more research needs to be done in order to better understand the components of CBD and how the compound functions with liposomes on a molecular level, it’s definitely a unique concept in the cannabis industry and one that’s worth keeping an eye on.